Associations of chemical composition and sources of PM2.5 with lung function of severe asthmatic adults in a low air pollution environment of urban Nagasaki, Japan.

Previous studies have linked ambient PM_2.5 to decreased pulmonary function, but the influence of specific chemical elements and emission sources on the severe asthmatic is not well understood. We examined the mass, chemical constituents, and sources of PM_2.5 for short-term associations with the pulmonary function of adults with severe asthma in a low air pollution environment in urban Nagasaki, Japan. We recruited 35 asthmatic adults and obtained the daily record of morning peak expiratory flow (PEF) in spring 2014-2016. PM_2.5 filters were extracted from an air quality monitoring station (178 days) and measured for 27 chemical elements. Source apportionment was performed using Positive Matrix Factorization (PMF).

We fitted generalized linear model with generalized estimating equation (GEE) method to estimate changes in PEF (from personal monthly maximum) and odds of severe respiratory deterioration (first ≥ 15% PEF reduction within a 1-week interval) associated with mass, constituents, and sources of PM_2.5, with adjustment for temperature and relative humidity.

EDTA
GE4011-100G	Glentham Life Sciences	100 g	EUR 48

EDTA
GE4011-1KG	Glentham Life Sciences	1 kg	EUR 84

EDTA
GE4011-250G	Glentham Life Sciences	250 g	EUR 54

EDTA
GE4011-500G	Glentham Life Sciences	500 g	EUR 64.8

EDTA
GE4011-1	Glentham Life Sciences	1	EUR 39.4

EDTA
GE4011-100	Glentham Life Sciences	100	EUR 11.3

EDTA
GE4011-250	Glentham Life Sciences	250	EUR 16.4

EDTA
GE4011-500	Glentham Life Sciences	500	EUR 23.8

0.5M EDTA
EDTA-150	BioAssay Systems	150 µL	EUR 15
Description: 0.5M EDTA used for preparation of urine samples for use with the Oxalate Quick Test Strips. Quantity: 150 µL 0.5M EDTA.

0.5M EDTA
E9000-010	GenDepot	100 ml	EUR 88.8

0.5M EDTA
E9000-050	GenDepot	500 ml	EUR 124.8

EDTA Na2
abx082384-500g	Abbexa	500 g	EUR 243.6

100G EDTA
NAT1090	Scientific Laboratory Supplies	100G	EUR 52.8

500G EDTA
NAT1092	Scientific Laboratory Supplies	500G	EUR 174

EDTA plasma
90-1009	Fitzgerald	100 ml	EUR 2433.6
Description: BNP and NT-proBNP free plasma EDTA

Trypsin (-EDTA)
abx098244-100ml	Abbexa	100 ml	EUR 493.2

EDTA Solution
2103-100	Biovision	each	EUR 164.4

EDTA, AM ester
19010	AAT Bioquest	10x50 ug	EUR 109

EDTA, AM ester
19011	AAT Bioquest	10 mg	EUR 166

EDTA, AM ester
19010-10x50ug	AAT Bioquest	10x50 ug	EUR 109
Description: Ethylenediaminetetraacetic acid (EDTA) might be the most popular metal ion chelator used for both industrial and medical purposes.

EDTA, AM ester
19011-10mg	AAT Bioquest	10 mg	EUR 166
Description: Ethylenediaminetetraacetic acid (EDTA) might be the most popular metal ion chelator used for both industrial and medical purposes.

Tris EDTA Saline, 10mM Tris HCl , 1mM EDTA, 2M Nacl
T8059-010	GenDepot	100ml	EUR 91.2

Tris EDTA Saline, 10mM Tris HCl , 1mM EDTA, 2M Nacl
T8059-050	GenDepot	500ml	EUR 100.8

Tris EDTA Saline, 10mM Tris HCl , 1mM EDTA, 2M Nacl
T8059-101	GenDepot	1L	EUR 151.2

Tris EDTA Saline, 10mM Tris HCl , 1mM EDTA, 2M Nacl
T8150-050	GenDepot	500 ml	EUR 100.8

Tris EDTA Saline, 10mM Tris HCl , 1mM EDTA, 2M Nacl
T8150-801	GenDepot	8L	EUR 144

Rabbit Plasma (EDTA)
88R-1029E	Fitzgerald	500 ml	EUR 276
Description: Sterile Rabbit Plasma with EDTA

CK PLASMA NS EDTA 500mL
33141-1	Pel-Freez	500mL	EUR 221.56

Pig PLASMA NS EDTA 500mL
39541-1	Pel-Freez	500mL	EUR 221.56

USP Sol. EDTA TS
USP2401	Scientific Laboratory Supplies	100ML	EUR 30

USP Sol. EDTA TS
USP2405	Scientific Laboratory Supplies	500ML	EUR 48

PEGylated Liposomal EDTA
PHPC002EDTA	ProFoldin	2 ml	EUR 140.62
Description: This product includes 2 ml of 30 mM EDTA encapsulated in 6 mg/ml liposomes in 0.1 M NaCl.

Rabbit PLASMA NS EDTA 500mL
31141-1	Pel-Freez	500mL	EUR 314.21

Rabbit PLASMA S EDTA 500mL
31156-1	Pel-Freez	500mL	EUR 342.91

Bovine PLASMA NS EDTA 500mL
37141-1	Pel-Freez	500mL	EUR 221.56

CP 0.1M EDTA Solution
CP8011	Scientific Laboratory Supplies	1L	EUR 27.6

1L EDTA 0.5M Solution
NAT1282	Scientific Laboratory Supplies	1L	EUR 183.6

EDTA, Ultra Pure, 1kg
R9410-1kg	ACTGene	each	EUR 228

Coagplas Rab Edta 3M
240827	Scientific Laboratory Supplies	PK10	EUR 95.31

CK WH BLOOD NS EDTA 500mL*
33131-1	Pel-Freez	500mL	EUR 282.89

Pig WH BLOOD NS EDTA 500mL*
39531-1	Pel-Freez	500mL	EUR 242.44

0.5 M EDTA, pH 8.0
GR103066	Genorise Scientific	100 mL	EUR 69

EDTA ferric sodium salt
GE7700-100G	Glentham Life Sciences	100 g	EUR 52.8

EDTA ferric sodium salt
GE7700-1KG	Glentham Life Sciences	1 kg	EUR 117.6

EDTA ferric sodium salt
GE7700-250G	Glentham Life Sciences	250 g	EUR 64.8

EDTA ferric sodium salt
GE7700-500G	Glentham Life Sciences	500 g	EUR 84

EDTA ferric sodium salt
GE7700-1	Glentham Life Sciences	1	EUR 67.2

EDTA ferric sodium salt
GE7700-100	Glentham Life Sciences	100	EUR 15.7

EDTA ferric sodium salt
GE7700-250	Glentham Life Sciences	250	EUR 23.8

EDTA ferric sodium salt
GE7700-500	Glentham Life Sciences	500	EUR 39.4

EDTA 0.5M Sterile Solution
SD8135	Bio Basic	450ml	EUR 86.1

USP Sol. 0.1 M EDTA
USP10115	Scientific Laboratory Supplies	500ML	EUR 60

Normal Feline Plasma (EDTA)
abx098254-50ml	Abbexa	50 ml	EUR 844.8

MicroMolar EDTA Assay kit
EDTA200	ProFoldin	200 assays	EUR 221.78
Description: This product includes 200 ul of 100 x C56 dye and 1000 ul of 1 mM EDTA. It is for measurement of 200 samples using 96-well plates. Cuvettes may also be used for measurements.

100mL 0.5M EDTA pH 8.0
46-034-CI	Scientific Laboratory Supplies	EACH	EUR 57.6

EDTA Buffer, 1X pH 8.0
18-155	Genesee Scientific	500ml/Unit	EUR 380

EDTA Buffer, 1X pH 8.0
18-156	Genesee Scientific	1000ml/Unit	EUR 427

EDTA, Disodium Salt, Dihydrate
CH032	ABM	500 g	EUR 195.6

EDTA, Disodium Salt, Dihydrate
CH033	ABM	1.0 kg	EUR 234

EDTA, Disodium Salt, Dihydrate
CH034	ABM	2.5 kg	EUR 400.8

EDTA disodium salt dihydrate
GE3023-100G	Glentham Life Sciences	100 g	EUR 48

EDTA disodium salt dihydrate
GE3023-1KG	Glentham Life Sciences	1 kg	EUR 84

EDTA disodium salt dihydrate
GE3023-250G	Glentham Life Sciences	250 g	EUR 55.2

EDTA disodium salt dihydrate
GE3023-500G	Glentham Life Sciences	500 g	EUR 64.8

EDTA disodium salt dihydrate
GE3023-5KG	Glentham Life Sciences	5 kg	EUR 180

EDTA, disodium salt, dihydrate
EB0185	Bio Basic	500g	EUR 84.01

EDTA disodium salt dihydrate
GE3023-1	Glentham Life Sciences	1	EUR 39.4

EDTA disodium salt dihydrate
GE3023-100	Glentham Life Sciences	100	EUR 11.3

EDTA disodium salt dihydrate
GE3023-250	Glentham Life Sciences	250	EUR 15.9

EDTA disodium salt dihydrate
GE3023-5	Glentham Life Sciences	5	EUR 118.7

EDTA disodium salt dihydrate
GE3023-500	Glentham Life Sciences	500	EUR 23.8

EDTA tetrasodium salt hydrate
GE3450-100G	Glentham Life Sciences	100 g	EUR 49.2

EDTA tetrasodium salt hydrate
GE3450-1KG	Glentham Life Sciences	1 kg	EUR 81.6

EDTA tetrasodium salt hydrate
GE3450-250G	Glentham Life Sciences	250 g	EUR 54

EDTA tetrasodium salt hydrate
GE3450-500G	Glentham Life Sciences	500 g	EUR 63.6

EDTA tetrasodium salt hydrate
GE3450-5KG	Glentham Life Sciences	5 kg	EUR 199.2

EDTA trisodium salt dihydrate
GE9701-100G	Glentham Life Sciences	100 g	EUR 64.8

EDTA trisodium salt dihydrate
GE9701-250G	Glentham Life Sciences	250 g	EUR 93.6

EDTA trisodium salt dihydrate
GE9701-500G	Glentham Life Sciences	500 g	EUR 141.6

EDTA tetrasodium salt hydrate
GE3450-1	Glentham Life Sciences	1	EUR 38

EDTA tetrasodium salt hydrate
GE3450-100	Glentham Life Sciences	100	EUR 11.8

EDTA tetrasodium salt hydrate
GE3450-250	Glentham Life Sciences	250	EUR 16.4

EDTA tetrasodium salt hydrate
GE3450-5	Glentham Life Sciences	5	EUR 134.4

EDTA tetrasodium salt hydrate
GE3450-500	Glentham Life Sciences	500	EUR 22.9

EDTA trisodium salt dihydrate
GE9701-100	Glentham Life Sciences	100	EUR 23.8

EDTA trisodium salt dihydrate
GE9701-250	Glentham Life Sciences	250	EUR 47.4

EDTA trisodium salt dihydrate
GE9701-500	Glentham Life Sciences	500	EUR 87.1

EDTA Solution 1.62% w/v
EDTA1625	Scientific Laboratory Supplies	5L	EUR 180

EDTA tetrasodium salt dihydrate
GK0795-100G	Glentham Life Sciences	100 g	EUR 48

EDTA tetrasodium salt dihydrate
GK0795-1KG	Glentham Life Sciences	1 kg	EUR 84

EDTA tetrasodium salt dihydrate
GK0795-2500G	Glentham Life Sciences	2500 g	EUR 141.6

EDTA tetrasodium salt dihydrate
GK0795-250G	Glentham Life Sciences	250 g	EUR 55.2

EDTA tetrasodium salt dihydrate
GK0795-500G	Glentham Life Sciences	500 g	EUR 63.6

EDTA dipotassium salt dihydrate
GE5635-100G	Glentham Life Sciences	100 g	EUR 64.8

EDTA dipotassium salt dihydrate
GE5635-250G	Glentham Life Sciences	250 g	EUR 88.8

EDTA dipotassium salt dihydrate
GE5635-500G	Glentham Life Sciences	500 g	EUR 122.4

EDTA, tetrasodium salt dihydrate
EB0436	Bio Basic	500g	EUR 105.94

EDTA, dipotassium salt, dihydrate
ED0075	Bio Basic	250g	EUR 99.67

EDTA dipotassium salt dihydrate
GE5635-100	Glentham Life Sciences	100	EUR 23.8

EDTA dipotassium salt dihydrate
GE5635-250	Glentham Life Sciences	250	EUR 43.5

EDTA dipotassium salt dihydrate
GE5635-500	Glentham Life Sciences	500	EUR 71.1

EDTA tetrasodium salt dihydrate
GK0795-1	Glentham Life Sciences	1	EUR 39.4

EDTA tetrasodium salt dihydrate
GK0795-100	Glentham Life Sciences	100	EUR 11.3

EDTA tetrasodium salt dihydrate
GK0795-250	Glentham Life Sciences	250	EUR 15.9

EDTA tetrasodium salt dihydrate
GK0795-2500	Glentham Life Sciences	2500	EUR 87.1

EDTA tetrasodium salt dihydrate
GK0795-500	Glentham Life Sciences	500	EUR 22.9

EDTA tripotassium salt dihydrate
GL1464-100G	Glentham Life Sciences	100 g	EUR 73.2

EDTA tripotassium salt dihydrate
GL1464-250G	Glentham Life Sciences	250 g	EUR 103.2

EDTA tripotassium salt dihydrate
GL1464-25G	Glentham Life Sciences	25 g	EUR 52.8

EDTA tripotassium salt dihydrate
GL1464-500G	Glentham Life Sciences	500 g	EUR 153.6

EDTA tripotassium salt dihydrate
GL1464-100	Glentham Life Sciences	100	EUR 30.9

EDTA tripotassium salt dihydrate
GL1464-25	Glentham Life Sciences	25	EUR 15.7

EDTA tripotassium salt dihydrate
GL1464-250	Glentham Life Sciences	250	EUR 55.4

EDTA tripotassium salt dihydrate
GL1464-500	Glentham Life Sciences	500	EUR 97.3

Rabbit WH BLOOD NS EDTA YG 500mL*
31131-1	Pel-Freez	500mL	EUR 314.21

Bovine MT WH BLOOD NS EDTA 500mL*
37131-1	Pel-Freez	500mL	EUR 242.44

EDTA, Iron (III), sodium salt
EB0437	Bio Basic	100g	EUR 78.79

EDTA solution, 0.5M in water
GE5993-500	Glentham Life Sciences	500	EUR 17.7

EDTA solution, 0.1M in water
GE7722-500	Glentham Life Sciences	500	EUR 16.6

Rabbit PLASMA NS K2 EDTA Y 500mL
31144-1	Pel-Freez	500mL	EUR 314.21

Rabbit PLASMA NS K3 EDTA YG 500mL
31145-1	Pel-Freez	500mL	EUR 280.27

EDTA zinc (II), disodium salt
EB6666	Bio Basic	100g	EUR 77.75

EDTA Disodium Salt 0.02m (0.04n)
ED20021	Scientific Laboratory Supplies	1L	EUR 157.2

EDTA copper(II) disodium salt
EB0434	Bio Basic	250g	EUR 100.72

0.25%Trypsin-0.04%EDTA Solution
TEDTA-10001	Cyagen	100mL	EUR 49

EDTA buffer pH 8.0, 1000 ml
12-9160-5	Medicago	1000 ml	EUR 315.6

EDTA buffer pH 8.0, 500 ml
12-9161-5	Medicago	500 ml	EUR 236.4

Dog Plasma (Sterile Sodium EDTA)
20-abx800113	Abbexa	EUR 1680.00 EUR 3951.60 EUR 1296.00	100 ml 500 ml 50 ml

Dog Plasma (Sterile Sodium EDTA)
abx800113-1L	Abbexa	1 L	EUR 6824.4

Goat Plasma (Sterile Sodium EDTA)
20-abx800038	Abbexa	EUR 794.40 EUR 994.80 EUR 678.00	100 ml 500 ml 50 ml

Goat Plasma (Sterile Sodium EDTA)
abx800038-1L	Abbexa	1 L	EUR 1195.2

EDTA disodium zinc salt hydrate
GX3802-100G	Glentham Life Sciences	100 g	EUR 64.8

EDTA disodium zinc salt hydrate
GX3802-250G	Glentham Life Sciences	250 g	EUR 90

EDTA disodium zinc salt hydrate
GX3802-25G	Glentham Life Sciences	25 g	EUR 51.6

EDTA disodium zinc salt hydrate
GX3802-500G	Glentham Life Sciences	500 g	EUR 132

EDTA disodium zinc salt hydrate
GX3802-100	Glentham Life Sciences	100	EUR 23.8

EDTA disodium zinc salt hydrate
GX3802-25	Glentham Life Sciences	25	EUR 13.9

EDTA disodium zinc salt hydrate
GX3802-250	Glentham Life Sciences	250	EUR 44.3

EDTA disodium zinc salt hydrate
GX3802-500	Glentham Life Sciences	500	EUR 79.1

Sheep Plasma (Sterile Sodium EDTA)
20-abx800023	Abbexa	EUR 794.40 EUR 994.80 EUR 678.00	100 ml 500 ml 50 ml

Sheep Plasma (Sterile Sodium EDTA)
abx800023-1L	Abbexa	1 L	EUR 1195.2

Horse Plasma (Sterile Sodium EDTA)
20-abx800053	Abbexa	EUR 1095.60 EUR 1378.80 EUR 927.60	100 ml 500 ml 50 ml

Horse Plasma (Sterile Sodium EDTA)
abx800053-1L	Abbexa	1 L	EUR 1779.6

Camel Plasma (Sterile Sodium EDTA)
20-abx800083	Abbexa	EUR 1980.00 EUR 4736.40 EUR 1545.60	100 ml 500 ml 50 ml

Camel Plasma (Sterile Sodium EDTA)
abx800083-1L	Abbexa	1 L	EUR 8110.8

10 x TBE (Tris/Borate/EDTA)
A00269	Bio Basic	500ml	EUR 67.63

Rabbit Plasma (Sterile Sodium EDTA)
20-abx800006	Abbexa	EUR 1880.40 EUR 4352.40 EUR 1378.80	100 ml 500 ml 50 ml

Rabbit Plasma (Sterile Sodium EDTA)
abx800006-1L	Abbexa	1 L	EUR 7509.6

Donkey Plasma (Sterile Sodium EDTA)
20-abx800068	Abbexa	EUR 1813.20 EUR 2348.40 EUR 1262.40	100 ml 500 ml 50 ml

Donkey Plasma (Sterile Sodium EDTA)
abx800068-1L	Abbexa	1 L	EUR 3066

Chicken Plasma (Sterile Sodium EDTA)
20-abx800128	Abbexa	EUR 978.00 EUR 2080.80 EUR 744.00	100 ml 500 ml 50 ml

Chicken Plasma (Sterile Sodium EDTA)
abx800128-1L	Abbexa	1 L	EUR 3567.6

EDTA disodium and monocalcium salt
EK014P2	Bio Basic	500g	EUR 115.33

100mL Trypsin EDTA 1x 0.05% Tryp
25-051-CI	Scientific Laboratory Supplies	PK6	EUR 81.6

500mL Trypsin EDTA 1x 0.05% Tryp
25-052-CV	Scientific Laboratory Supplies	PK6	EUR 259.2

EDTA magnesium disodium salt hydrate
GE3956-100G	Glentham Life Sciences	100 g	EUR 79.2

EDTA magnesium disodium salt hydrate
GE3956-1KG	Glentham Life Sciences	1 kg	EUR 294

EDTA magnesium disodium salt hydrate
GE3956-250G	Glentham Life Sciences	250 g	EUR 122.4

EDTA magnesium disodium salt hydrate
GE3956-25G	Glentham Life Sciences	25 g	EUR 54

EDTA magnesium disodium salt hydrate
GE3956-500G	Glentham Life Sciences	500 g	EUR 184.8

EDTA manganese disodium salt hydrate
GX6009-100G	Glentham Life Sciences	100 g	EUR 122.4

EDTA manganese disodium salt hydrate
GX6009-250G	Glentham Life Sciences	250 g	EUR 208.8

EDTA manganese disodium salt hydrate
GX6009-25G	Glentham Life Sciences	25 g	EUR 69.6

EDTA manganese disodium salt hydrate
GX6009-500G	Glentham Life Sciences	500 g	EUR 322.8

EDTA disodium and monomagnesium salt
EB0435	Bio Basic	500g	EUR 133.08

EDTA manganese disodium salt hydrate
GX6009-100	Glentham Life Sciences	100	EUR 71.1

EDTA manganese disodium salt hydrate
GX6009-25	Glentham Life Sciences	25	EUR 27.8

EDTA manganese disodium salt hydrate
GX6009-250	Glentham Life Sciences	250	EUR 142.4

EDTA manganese disodium salt hydrate
GX6009-500	Glentham Life Sciences	500	EUR 237.2

EDTA magnesium disodium salt hydrate
GE3956-1	Glentham Life Sciences	1	EUR 213.7

EDTA magnesium disodium salt hydrate
GE3956-100	Glentham Life Sciences	100	EUR 35.5

EDTA magnesium disodium salt hydrate
GE3956-25	Glentham Life Sciences	25	EUR 16.4

EDTA magnesium disodium salt hydrate
GE3956-250	Glentham Life Sciences	250	EUR 71.1

EDTA magnesium disodium salt hydrate
GE3956-500	Glentham Life Sciences	500	EUR 122.6

EDTA Buffer, 0, 5M , 1X, pH 8.0,
USD8135	Bio Basic	500ml	EUR 86.1

Protease Inhibition Cocktail with EDTA
G135E	ABM	1.0 ml	EUR 200.4

BD Vacutainer EDTA K3 3.0ml 13x75mm
368857	Scientific Laboratory Supplies	PK1000	EUR 207.6

Non-sterile rat plasma with EDTA
RTPE07-0050	Equitech	50 ml	EUR 293.28

Non-sterile rat plasma with EDTA
RTPE07-0100	Equitech	100 ml	EUR 360.36

Non-sterile rat plasma with EDTA
RTPE07-0500	Equitech	500 ml	EUR 581.88

Dog Whole Blood (Sterile Sodium EDTA)
20-abx800119	Abbexa	EUR 744.00 EUR 526.80	100 ml 50 ml

Non-sterile goat plasma with EDTA
GPE07-0100	Equitech	100 ml	EUR 198.12

Non-sterile goat plasma with EDTA
GPE07-0500	Equitech	500 ml	EUR 227.76

Goat Whole Blood (Sterile Sodium EDTA)
20-abx800044	Abbexa	EUR 376.80 EUR 326.40	100 ml 50 ml

Dog Plasma (Non-Sterile Sodium EDTA)
20-abx800112	Abbexa	EUR 1312.80 EUR 3066.00 EUR 994.80	100 ml 500 ml 50 ml

Dog Plasma (Non-Sterile Sodium EDTA)
abx800112-1L	Abbexa	1 L	EUR 5137.2

Non-sterile mouse plasma with EDTA
MPE07-0050	Equitech	50 ml	EUR 293.28

Non-sterile mouse plasma with EDTA
MPE07-0100	Equitech	100 ml	EUR 360.36

Non-sterile mouse plasma with EDTA
MPE07-0500	Equitech	500 ml	EUR 762.84

DiagNano EDTA Silica Particles, 300 nm
DNG-F112	Creative Diagnostics	10 mL	EUR 745.2

DiagNano EDTA Silica Particles, 500 nm
DNG-F113	Creative Diagnostics	10 mL	EUR 745.2

DiagNano EDTA Silica Particles, 1 μm
DNG-F114	Creative Diagnostics	10 mL	EUR 745.2

DiagNano EDTA Silica Particles, 1.5 μm
DNG-F115	Creative Diagnostics	10 mL	EUR 745.2

DiagNano EDTA Silica Particles, 3 μm
DNG-F116	Creative Diagnostics	10 mL	EUR 745.2

DiagNano EDTA Silica Particles, 4 μm
DNG-F117	Creative Diagnostics	10 mL	EUR 745.2

DiagNano EDTA Silica Particles, 5 μm
DNG-F118	Creative Diagnostics	10 mL	EUR 745.2

DiagNano EDTA Silica Particles, 10 μm
DNG-F119	Creative Diagnostics	10 mL	EUR 764.4

DiagNano EDTA Silica Particles, 15 μm
DNG-F120	Creative Diagnostics	10 mL	EUR 764.4

DiagNano EDTA Silica Particles, 20 μm
DNG-F121	Creative Diagnostics	10 mL	EUR 770.4

Constituent sulfate (SO₄^2-) and PM_2.5 from oil combustion and traffic were associated with reduced PEF. An interquartile range (IQR) increase in SO₄^2- (3.7 μg/m³, average lags 0-1) was associated with a decrease of 0.38% (95% confidence interval = -0.75% to -0.001%). An IQR increase in oil combustion and traffic-sourced PM_2.5 (2.64 μg/m³, lag 1) was associated with a decrease of 0.33% (-0.62% to -0.002%).

We found a larger PEF decrease associated with PM_2.5 from dust/soil on Asian Dust days. There was no evidence linking total mass and metals to reduced pulmonary function. The ventilatory capacity of adults with severe asthma is susceptible to specific constituents/sources of PM_2.5 such as sulfate and oil combustion and traffic despite active self-management of asthma and low air pollution levels in the study location.